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Updated: Jun 30, 2026

In Vitro Assay of Bacterial Adhesion onto Mammalian Epithelial Cells
Published on: May 16, 2011
The phosphate transport system of enteropathogenic Escherichia coli is involved in adherence to the host
Romney M Hyland1, Glen D Armstrong
1Department of Microbiology & Infectious Diseases, University of Calgary, Calgary, Alberta, Canada. rmhyland@ucalgary.ca
Abstract:
Evaluation of: Ferreira GM, Spira B: The pst operon of enteropathogenic Escherichia coli enhances bacterial adherence to epithelial cells. Microbiology 154(7), 2025-2036 (2008). Enteropathogenic Escherichia coli (EPEC) colonization of the human intestinal epithelium constitutes a complex, two-stage process, which involves multiple virulence factors that are expressed in response to numerous environmental signals. Ferreira and Spira present evidence that the phosphate transport system is involved in regulating EPEC colonization in a novel manner that does not appear to involve inorganic phosphate sensing.
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