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Updated: Jun 30, 2026

Culture of Bladder Cancer Organoids as Precision Medicine Tools
08:39

Culture of Bladder Cancer Organoids as Precision Medicine Tools

Published on: December 28, 2021

Bladder cancer subtypes defined by genomic alterations.

Margaret A Knowles1

  • 1Cancer Research UK Clinical Centre, Leeds Institute for Molecular Medicine, St James's University Hospital, Beckett Street, Leeds, UK. m.a.knowles@leeds.ac.uk

Scandinavian Journal of Urology and Nephrology. Supplementum
|December 5, 2008
PubMed
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Understanding genomic alterations in bladder cancer is key. This review details molecular changes in transitional cell carcinoma, aiming for better prediction of recurrence, progression, and personalized therapies.

Area of Science:

  • Oncology
  • Genetics
  • Urology

Background:

  • Bladder tumors are diverse in pathology and behavior.
  • Current methods for predicting bladder cancer recurrence, progression, and treatment response lack precision.
  • Molecular insights are needed for improved prediction and individualized therapies.

Purpose of the Study:

  • To review the current knowledge of genomic alterations in bladder transitional cell carcinoma.
  • To explore molecular changes in precursor lesions of bladder cancer.

Main Methods:

  • Literature review of genomic alterations in bladder cancer.
  • Summary of current research on molecular changes in transitional cell carcinoma and precursor lesions.

Main Results:

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An Orthotopic Bladder Cancer Model for Gene Delivery Studies
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An Orthotopic Bladder Cancer Model for Gene Delivery Studies

Published on: December 1, 2013

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Last Updated: Jun 30, 2026

Culture of Bladder Cancer Organoids as Precision Medicine Tools
08:39

Culture of Bladder Cancer Organoids as Precision Medicine Tools

Published on: December 28, 2021

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
07:48

An Orthotopic Bladder Cancer Model for Gene Delivery Studies

Published on: December 1, 2013

  • Genomic alterations play a crucial role in bladder cancer development and progression.
  • Knowledge of these alterations can enhance predictive power for clinical outcomes.
  • This understanding facilitates the development of novel, individualized treatment strategies.

Conclusions:

  • Detailed knowledge of genomic alterations in bladder cancer is essential for improving patient outcomes.
  • Further research into molecular changes will enable more accurate prognostication and targeted therapies.
  • Individualized treatment approaches based on molecular profiles hold promise for bladder cancer management.