Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 30, 2026

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

Electronic control of elastomeric microfluidic circuits with shape memory actuators.

Saurabh Vyawahare1, Suresh Sitaula, Sujitha Martin

  • 1Kavli Nanoscience Institute, California Institute of Technology, Pasadena, CA 91125, USA. saurabhv@caltech.edu

Lab on a Chip
|September 27, 2008
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Plasmonic Moiré Superlattices for Robust Nanogap Cluster Formation.

Small methods·2026
Same author

Autofluorescence Virtual Staining System for H&E Histology and Multiplex Immunofluorescence Applied to Immuno-Oncology Biomarkers in Lung Cancer.

Cancer research communications·2024
Same author

Patterned thin film enzyme electrodes <i>via</i> spincoating and glutaraldehyde vapor crosslinking: towards scalable fabrication of integrated sensor-on-CMOS devices.

Lab on a chip·2024
Same author

Novel Deposition Method of Crosslinked Polyethylene Thin Film for Low-Refractive-Index Mid-Infrared Optical Coatings.

Sensors (Basel, Switzerland)·2023
Same author

Sorting droplets into many outlets.

Lab on a chip·2021
Same author

Plasma-Etched Pattern Transfer of Sub-10 nm Structures Using a Metal-Organic Resist and Helium Ion Beam Lithography.

Nano letters·2019
Same journal

Tunable self-assembling cellular microarray for single-neutrophil vital and suicidal extracellular traps.

Lab on a chip·2026
Same journal

Precise programmable tumor cell subpopulation sorting <i>via</i> an electromagnetic microfluidic platform.

Lab on a chip·2026
Same journal

Bridging dimensions: combining one- and two-photon 3D printing for microfluidic device fabrication.

Lab on a chip·2026
Same journal

Microfluidic rare cell analysis beyond counting: workflow design from enrichment to multi-omics.

Lab on a chip·2026
Same journal

A sperm racetrack to separate sperm by swim speed.

Lab on a chip·2026
Same journal

Controlled encapsulation and droplet size prediction in two-step microfluidic double emulsions.

Lab on a chip·2026
See all related articles

Researchers integrated microfluidic circuits with shape memory alloys (SMAs) for electronic control. This breakthrough enables miniaturized, high-density microfluidic systems, paving the way for portable, high-throughput applications.

Area of Science:

  • Microfluidics and MEMS
  • Materials Science (Shape Memory Alloys)
  • Electrical Engineering (Integrated Circuits)

Background:

  • Sophisticated microfluidic circuits are fabricated using multi-layer soft-lithography.
  • Current microfluidic systems suffer from bulky external actuation and interfacing elements (e.g., solenoids, pins).
  • This size mismatch hinders large-scale integration and the development of portable, high-throughput microfluidic devices.

Purpose of the Study:

  • To miniaturize the actuation and control elements of microfluidic circuits.
  • To enable electronic activation and integration of microfluidic components.
  • To develop a control architecture for high-density microfluidic systems analogous to integrated circuits.

Main Methods:

  • Combined multi-layer soft-lithography with shape memory alloys (SMAs).

More Related Videos

Microfluidic Preparation of Liquid Crystalline Elastomer Actuators
12:04

Microfluidic Preparation of Liquid Crystalline Elastomer Actuators

Published on: May 20, 2018

Fabrication Process of Silicone-based Dielectric Elastomer Actuators
10:32

Fabrication Process of Silicone-based Dielectric Elastomer Actuators

Published on: February 1, 2016

Related Experiment Videos

Last Updated: Jun 30, 2026

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

Microfluidic Preparation of Liquid Crystalline Elastomer Actuators
12:04

Microfluidic Preparation of Liquid Crystalline Elastomer Actuators

Published on: May 20, 2018

Fabrication Process of Silicone-based Dielectric Elastomer Actuators
10:32

Fabrication Process of Silicone-based Dielectric Elastomer Actuators

Published on: February 1, 2016

  • Developed electronically activated microfluidic components: valves, pumps, latches, and multiplexers.
  • Assembled components on printed circuit boards (PCBs) for integration with opto-electronic elements.
  • Introduced the concept of 'microfluidic states' for simplified control.

    • Main Results:

    • Demonstrated functional microfluidic components controlled by SMAs, enabling electronic activation.
    • Achieved integration of high-density microfluidic chips onto PCBs alongside standard electronic components.
    • Proposed a control architecture reducing external control lines logarithmically through microfluidic states.

    Conclusions:

    • The integration of SMAs with microfluidics overcomes previous size limitations for control elements.
    • This approach facilitates the creation of compact, electronically controlled microfluidic systems.
    • The developed technology and control architecture bring microfluidics closer to the physical and abstract models of electronic integrated circuits.