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Published on: June 23, 2023
Statin use and the risk of Parkinson disease: a nested case control study
Ali Samii1, Bruce C Carleton, Mahyar Etminan
1Department of Neurology, University of Washington, Seattle VA Parkinson Disease Research Education and Clinical Center (PADRECC), VA Puget Sound Health Care System, 1660 S. Columbian Way, MS-127, Seattle, WA 98108, USA. asamii@u.washington.edu
Abstract:
Using the British Columbia Linked Health Databases, we explored the association between the use of statin drugs and the risk of developing Parkinson disease (PD). We followed a cohort of older adults in the Province of British Columbia from 1997 to 2003. Using a study design of nested case control (case-control study within a cohort), the relative risk of developing PD for statin users was 0.94 (0.82-1.09). Our study did not show a statistically significant effect on the risk of PD with statin use.
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