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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
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Migraine and stroke: current perspectives

Debra Elliott1

  • 1Department of Neurology, Louisiana State University Health Sciences Center, Shreveport, LA 71130-3932, USA. delli1@Isuhsc.edu

Neurological Research
|October 2, 2008
PubMed
Abstract

Insights

Migraine, particularly with aura, is a risk factor for stroke, with the posterior circulation being most vulnerable. Understanding these associations is expanding, though true migrainous infarction remains rare.

Area of Science:

  • Neurology
  • Cerebrovascular Medicine
  • Neuroimaging

Background:

  • Migraine is a common neurological disorder with complex associations to cerebrovascular events.
  • Understanding the link between migraine and ischemic stroke is crucial for patient management and risk assessment.

Purpose of the Study:

  • To review current concepts linking migraine and ischemic stroke.
  • To examine focal neurological deficits and MRI findings in migraine patients.

Main Methods:

  • A comprehensive literature search was performed using PubMed.
  • Keywords included "migraine" and "ischemic stroke" to identify relevant neurological studies.

Main Results:

  • Migraine, especially with aura, is a recognized risk factor for stroke, with the posterior circulation being most affected.
  • Potential mechanisms include cortical spreading depression, vasospasm, endothelial dysfunction, and genetic factors.
  • While rare, stroke associated with migraine treatments can occur under specific circumstances.

Conclusions:

  • True migrainous infarction is infrequent.
  • The relationship between migraine and cerebrovascular behavior is increasingly understood.

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