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Hemorrhagic Stroke ll: Pathophysiology

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...

Ischemic Stroke ll: Pathophysiology

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...

Stroke: Introduction and Types

Stroke: Introduction and Types

A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...

Ischemic Stroke l: Introduction

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.

Hemorrhagic Stroke l: Introduction

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...

Transient Ischemic Attack l: Introduction

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...

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Updated: Jun 29, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

Migraine and stroke: current perspectives.

Debra Elliott¹

¹Department of Neurology, Louisiana State University Health Sciences Center, Shreveport, LA 71130-3932, USA. delli1@Isuhsc.edu

Neurological Research

|October 2, 2008

Summary

This summary is machine-generated.

Migraine, particularly with aura, is a risk factor for stroke, with the posterior circulation being most vulnerable. Understanding these associations is expanding, though true migrainous infarction remains rare.

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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

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Published on: August 18, 2015

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

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Published on: July 29, 2021

Area of Science:

Neurology
Cerebrovascular Medicine
Neuroimaging

Background:

Migraine is a common neurological disorder with complex associations to cerebrovascular events.
Understanding the link between migraine and ischemic stroke is crucial for patient management and risk assessment.

Purpose of the Study:

To review current concepts linking migraine and ischemic stroke.
To examine focal neurological deficits and MRI findings in migraine patients.

Main Methods:

A comprehensive literature search was performed using PubMed.
Keywords included "migraine" and "ischemic stroke" to identify relevant neurological studies.

Main Results:

Migraine, especially with aura, is a recognized risk factor for stroke, with the posterior circulation being most affected.
Potential mechanisms include cortical spreading depression, vasospasm, endothelial dysfunction, and genetic factors.
While rare, stroke associated with migraine treatments can occur under specific circumstances.

Conclusions:

True migrainous infarction is infrequent.
The relationship between migraine and cerebrovascular behavior is increasingly understood.