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Updated: Jun 29, 2026

A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse
Published on: October 24, 2017
Prenatal three-dimensional ultrasonography in a case of agnathia-otocephaly
Patou Tantbirojn1, Mana Taweevisit, Suchila Sritippayawan
1Department of Obstetrics, Chulalongkorn University, Bangkok, Thailand. two_devil@hotmail.com
Abstract:
A case of prenatally diagnosed agnathia-otocephaly is reported. Agnathia is an extremely rare anomaly characterized by an absence or hypoplasia of the mandible and abnormal horizontal position of the ears. The targeted 2-D ultrasonography at 24 weeks of gestation revealed abnormal lower facial profile. Surface rendering 3-D ultrasonography was used to evaluate the facial feature, showing excellent image when compared to the fetal face at autopsy. The reported case is discussed with a short review of the literature.
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