Related Experiment Video
Updated: Jun 29, 2026
11:49
Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
Published on: March 8, 2019
[Clinical application of AcrySof ReStor multifocal intraocular lens]
Jian Ye1, Xiao-fan Chen, Chun-lin Chen
1Department of Ophthalmology, Research Institute of Surgery, Daping Hospital of the Third Military Medical University, Chongqing 400042, China. yejian1979@163.com
[Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology
|October 11, 2008
Summary
AcrySof ReStor multifocal intraocular lens (MIOL) implantation significantly improves uncorrected near vision after cataract surgery. Most patients achieved spectacle independence, enhancing their quality of life.
Area of Science:
- Ophthalmology
- Biomedical Engineering
- Retinal Surgery
Background:
- Cataract surgery aims to restore vision by replacing the clouded natural lens.
- Multifocal intraocular lenses (MIOLs) offer the potential for improved uncorrected vision at multiple distances.
Purpose of the Study:
- To evaluate the clinical outcomes of AcrySof ReStor multifocal intraocular lens (MIOL) implantation post-cataract surgery.
- To compare the efficacy of MIOL with single-focus intraocular lenses (SIOLs) in terms of visual acuity and patient satisfaction.
Main Methods:
- A non-randomized comparative clinical study involving 52 eyes (22 cases with MIOL, 30 eyes with SIOL).
- Phacoemulsification with small incision was performed, followed by implantation of either AcrySof ReStor MIOL or SIOL.
- Outcomes assessed included visual acuity, corneal astigmatism, complications, spectacle independence, and patient satisfaction over a 3-14 month follow-up.
Main Results:
- 86.7% of patients with MIOL achieved uncorrected near visual acuity of 0.5 or better, compared to 33.3% with SIOL (P < 0.05).
- 66.7% of MIOL patients achieved uncorrected near visual acuity of 1.0 or better, versus 0% with SIOL (P < 0.05).
- Spectacle independence was achieved in 86.7% of MIOL cases versus 13.3% of SIOL cases; no significant differences in corrected visual acuities or astigmatism were noted.
Conclusions:
- AcrySof ReStor MIOL implantation significantly enhances uncorrected near and distant vision following cataract surgery.
- The MIOL leads to a high rate of spectacle independence and improved patient quality of life.
- While effective, potential complications like elevated intraocular pressure require monitoring.
Related Concept Videos
01:27Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
01:28Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...