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Reversible transdifferentiation in the adipose organ

Saverio Cinti1

  • 1Istituto di Morfologia Umana Normale, Università Politecnica delle Marche, Ancona.

International Journal of Pediatric Obesity : IJPO : an Official Journal of the International Association for the Study of Obesity
|December 17, 2008
PubMed
Summary

No abstract available in PubMed .

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Related Concept Videos

Forced Transdifferentiation01:28

Forced Transdifferentiation

Transdifferentiation, also known as lineage reprogramming, was first discovered by Selman and Kafatos in 1974 in silkmoths. They observed that the moths’ cuticle-producing cells transformed into salt-producing cells. Many such cases of natural transdifferentiation occur in organisms. In humans, pancreatic alpha cells can become beta cells. In newts, the loss of the eye’s lens causes the pigmented epithelial cells to transdifferentiate into the lens cells.
Artificial transdifferentiation occurs...