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Related Concept Videos

Surface Active Agents01:27

Surface Active Agents

Surfactants, named for their behavior at interfaces, positively adsorb at the interfaces of two phases, reducing interfacial tension. Their versatility as emulsifiers, detergents, and foaming agents stems from this ability. Surfactants, often termed amphiphiles, share the property of amphipathy, with molecules having both hydrophilic and hydrophobic portions. The hydrophilic part is called the head, and the hydrophobic part, including an elongated alkyl substituent, forms the tail.Surfactants...
Micelles01:30

Micelles

Micelle formation is an intricate process that hinges on the properties of amphiphilic or amphipathic molecules and the conditions of the system in which they are found. Amphiphilic molecules, which have both hydrophilic (water-attracting) and hydrophobic (water-repelling) parts, play a critical role in this process.In aqueous environments, these molecules arrange themselves such that their hydrophilic heads are turned towards the water phase, while their hydrophobic tails are oriented away...
Colloids03:22

Colloids

Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles that are visible to the naked eye or can be seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. On the other hand, a solution is a homogeneous mixture in which no settling occurs and in which the dissolved...
Solubility03:00

Solubility

Solution, Solubility, and Solubility Equilibrium
A solution is a homogeneous mixture composed of a solvent, the major component, and a solute, the minor component. The physical state of a solution—solid, liquid, or gas—is typically the same as that of the solvent. Solute concentrations are often described with qualitative terms such as dilute (of relatively low concentration) and concentrated (of relatively high concentration).
In a solution, the solute particles (molecules, atoms, and/or ions)...
Detergent Purification of Membrane Proteins01:18

Detergent Purification of Membrane Proteins

Detergents are used to purify the integral proteins of the membrane. The hydrophobic portion of the detergent can replace membrane phospholipids while solubilizing the membrane proteins. When detergent monomers reach a specific concentration in a solution called critical micelle concentration (CMC), they form micelles. Above CMC, the concentration of the detergent monomers remains in equilibrium with the micelle. The number of detergent monomers present in the CMC varies for each detergent, and...
Colloidal precipitates01:09

Colloidal precipitates

The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...

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Related Experiment Video

Updated: Jun 29, 2026

Detergent-free Ultrafast Reconstitution of Membrane Proteins into Lipid Bilayers Using Fusogenic Complementary-charged Proteoliposomes.
11:10

Detergent-free Ultrafast Reconstitution of Membrane Proteins into Lipid Bilayers Using Fusogenic Complementary-charged Proteoliposomes.

Published on: April 5, 2018

Repulsion between inorganic particles inserted within surfactant bilayers.

Doru Constantin1, Brigitte Pansu, Marianne Impéror

  • 1Laboratoire de Physique des Solides, Université Paris-Sud, CNRS, UMR8502, 91405 Orsay Cedex, France. constantin@lps.u-psud.fr

Physical Review Letters
|October 15, 2008
PubMed
Summary
This summary is machine-generated.

We measured the repulsive interaction between hydrophobic particles within surfactant bilayers using synchrotron small-angle x-ray scattering. This reveals key insights into particle interactions in membranes.

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Last Updated: Jun 29, 2026

Detergent-free Ultrafast Reconstitution of Membrane Proteins into Lipid Bilayers Using Fusogenic Complementary-charged Proteoliposomes.
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Detergent-free Ultrafast Reconstitution of Membrane Proteins into Lipid Bilayers Using Fusogenic Complementary-charged Proteoliposomes.

Published on: April 5, 2018

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Assembly of Cell Mimicking Supported and Suspended Lipid Bilayer Models for the Study of Molecular Interactions
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Assembly of Cell Mimicking Supported and Suspended Lipid Bilayer Models for the Study of Molecular Interactions

Published on: August 3, 2021

Area of Science:

  • Materials Science
  • Biophysics
  • Physical Chemistry

Background:

  • Zwitterionic surfactants form lamellar phases, crucial for biological membranes.
  • Hydrophobic particles can act as model inclusions within lipid bilayers.
  • Understanding interactions between membrane components is vital for cell biology.

Purpose of the Study:

  • To quantify the membrane-mediated interaction between hydrophobic inorganic particles in a zwitterionic surfactant lamellar phase.
  • To investigate the effect of particle concentration on particle interactions within the membrane.
  • To establish a method for studying interactions between membrane inclusions.

Main Methods:

  • Synchrotron small-angle x-ray scattering (SAXS) was used to study highly aligned lamellar phases.
  • Monodisperse, spherical hydrophobic inorganic particles were doped into the surfactant lamellar phase.
  • Analysis of the 2D fluid structure factor of the particles provided interaction data.

Main Results:

  • The interaction between the membrane-mediated particles was found to be repulsive.
  • The contact value of the repulsive interaction was determined to be approximately 4kBT.
  • The range of this repulsive interaction was measured to be 14 angstroms.

Conclusions:

  • Hydrophobic particle interactions within surfactant bilayers are repulsive.
  • The SAXS technique provides a powerful tool to study membrane inclusion interactions.
  • This research contributes to understanding the behavior of molecules and particles within biological membranes.