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Related Experiment Video

Updated: Jun 29, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

Ventricular dyssynchrony index: comparison with two-dimensional and three-dimensional ejection fraction.

Marcelo L C Vieira¹, Alexandre F Cury, Naccarato Gustavo

¹Hospital Israelita Albert Einstein, São Paulo, SP, Brasil.

Arquivos Brasileiros De Cardiologia

|October 15, 2008

Summary

Left ventricular electromechanical coupling (LV sync) assessed by 3D echocardiography (ECHO) strongly correlates with left ventricular ejection fraction (LVEF) measured by both 3D and 2D ECHO in patients with heart failure.

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Last Updated: Jun 29, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

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Area of Science:

Cardiology
Medical Imaging
Biomedical Engineering

Background:

Left ventricular (LV) electromechanical coupling (synchrony) is crucial for assessing systolic performance.
It is particularly important for guiding cardiac resynchronization therapy in advanced congestive heart failure (CHF).

Purpose of the Study:

To compare LV synchrony analysis using real-time 3D echocardiography (ECHO) with left ventricular ejection fraction (LVEF) measurements.
To evaluate the correlation between LV synchrony and LVEF obtained via 2D and 3D ECHO.

Main Methods:

A prospective study included 92 individuals (60 normal, 32 with dilated cardiomyopathy).
3D ECHO was used to measure LVEF, volumes, and the dyssynchrony index (%DI) for 16 LV segments.
2D ECHO measured LVEF (Simpson's method) and LV systolic/diastolic volumes.

Main Results:

The dyssynchrony index (%DI) ranged from 0.2900 to 28.1000.
3D LVEF ranged from 0.17 to 0.81, and 2D LVEF ranged from 0.3 to 0.69.
A significant negative correlation was found between %DI and 3D LVEF (r=-0.7432, p<0.0001) and between %DI and 2D LVEF (r=-0.7012, p<0.0001).

Conclusions:

A strong negative correlation exists between LV electromechanical synchrony and LVEF.
Echocardiography (both 3D and 2D) effectively measures this relationship.
These findings support the utility of 3D ECHO in assessing LV function and synchrony.