Related Experiment Video
Updated: Jun 28, 2026

11:24
Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy
Published on: October 18, 2011
Cranial radiation therapy and damage to hippocampal neurogenesis
1Department of Neurology, Stanford University, Stanford Advanced Medicine Center, Palo Alto, California 94305, USA. mmonje@stanford.edu
Developmental Disabilities Research Reviews
|October 17, 2008
Abstract:
Cranial radiation therapy is associated with a progressive decline in cognitive function, prominently memory function. Impairment of hippocampal neurogenesis is thought to be an important mechanism underlying this cognitive decline. Recent work has elucidated the mechanisms of radiation-induced failure of neurogenesis. Potential therapeutic interventions are emerging.

