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Updated: Jun 28, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
[Dysphagia with no apparent cause]
Mohamed Merrouche1, Anne-Laure Pelletier
1Service d'hépato-gastroentérologie, CHU Bichat-Claude-Bernard, Université Paris-Diderot Paris-7, 75877 Paris Cedex 18.
Dysphagia, difficulty swallowing, often diagnosed through patient history. Eosinophilic esophagitis and achalasia require specific diagnostic tests like endoscopy and esophageal manometry.
Area of Science:
- Gastroenterology
- Otolaryngology
Context:
- Dysphagia presents as a symptom of various oropharyngeal and esophageal conditions, both benign and malignant.
- Accurate etiological determination is frequently achievable through detailed patient history alone.
Purpose:
- To outline the diagnostic approaches for dysphagia.
- To highlight key conditions and diagnostic tools for swallowing disorders.
Summary:
- A thorough patient history is crucial for diagnosing dysphagia.
- Eosinophilic esophagitis should be considered in cases with normal endoscopic findings.
- Esophageal manometry is essential for diagnosing achalasia.
Impact:
- Improved diagnostic accuracy for dysphagia.
- Timely identification of specific swallowing disorders.
- Guidance for clinicians in managing dysphagia patients.
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