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Development of evidence-based clinical practice guidelines (CPGs): comparing approaches.
Tari Turner1, Marie Misso, Claire Harris
1Centre for Clinical Effectiveness, Southern Health, Locked Bag 29, Clayton, Victoria, 3168, Australia. tari.turner@med.monash.edu.au
Implementation Science : IS
|October 29, 2008
Summary
Clinical practice guidelines (CPGs) development handbooks show strong agreement on essential elements. However, further research is needed to understand why these key components are not always followed by CPG developers.
Area of Science:
- Health Services Research
- Evidence-Based Medicine
- Guideline Development
Background:
- Clinical practice guidelines (CPGs) have the potential to improve healthcare but are often poorly developed and implemented.
- Effective CPG development and implementation are crucial for enhancing clinical practice and patient outcomes.
- There is a need to assess the consistency and adequacy of guidance in existing CPG development resources.
Purpose of the Study:
- To determine consensus on fundamental characteristics of evidence-based CPG development processes.
- To evaluate if current CPG development handbooks offer sufficient practical guidance for users.
- To identify key elements consistently addressed across major CPG development resources.
Main Methods:
- A systematic search identified six key CPG development handbooks from national and international organizations.
- A checklist of 14 essential elements for CPG development was created.
- Two reviewers assessed each handbook for the presence and clarity of guidance on each element.
Main Results:
- Six major CPG development handbooks were analyzed (Council of Europe, Australia NHMRC, UK NICE, NZGG, SIGN, WHO).
- Strong concordance was found among handbooks regarding essential elements of evidence-based CPG development.
- All analyzed handbooks emphasize multidisciplinary groups, consumer involvement, systematic evidence searching/appraisal, recommendation drafting, external consultation, and regular updates.
Conclusions:
- Existing CPG development handbooks demonstrate significant agreement on core components of an evidence-based process.
- Despite concordance in handbooks, gaps likely exist in actual CPG development practices.
- Further investigation is warranted to understand the discrepancy between recommended practices and their application by CPG developers.
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