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Related Concept Videos

Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
Primary Lymphoid Organs01:16

Primary Lymphoid Organs

Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
Lymphoid Cells and Tissues01:18

Lymphoid Cells and Tissues

Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
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Detailed Structure and Function of Lymph Nodes01:23

Detailed Structure and Function of Lymph Nodes

Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
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Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
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Published on: March 30, 2018

Marginal zone lymphomas.

Emanuele Zucca1, Francesco Bertoni, Anastasios Stathis

  • 1Oncology Institute of Southern Switzerland, Ospedale San Giovanni, 6500 Bellinzona, Switzerland. ielsg@ticino.com

Hematology/Oncology Clinics of North America
|October 29, 2008
PubMed
Summary
This summary is machine-generated.

This article reviews the three main types of marginal zone lymphomas: extranodal, nodal, and splenic. It provides an overview of these distinct B-cell lymphomas within the WHO classification.

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Published on: November 26, 2018

Area of Science:

  • Hematology
  • Oncology
  • Pathology

Background:

  • The World Health Organization classification categorizes tumors of hematopoietic and lymphoid tissues.
  • Marginal zone lymphomas represent a specific group within these classifications.
  • This group includes distinct entities affecting different anatomical sites.

Purpose of the Study:

  • To provide a comprehensive overview of marginal zone lymphomas.
  • To detail the three main entities classified under marginal zone lymphomas.
  • To clarify the classification and characteristics of these B-cell lymphomas.

Main Methods:

  • Review of the World Health Organization classification of tumors of hematopoietic and lymphoid tissues.
  • Analysis of the defining characteristics of extranodal, nodal, and splenic marginal zone lymphomas.
  • Synthesis of information on marginal zone B-cell lymphomas, including those with circulating villous lymphocytes.

Main Results:

  • Identification of three primary marginal zone lymphoma entities: extranodal (MALT lymphoma), nodal, and splenic.
  • Differentiation based on anatomical location and specific pathological features.
  • Inclusion of splenic marginal zone lymphoma with or without circulating villous lymphocytes as a distinct category.

Conclusions:

  • Marginal zone lymphomas are a heterogeneous group of B-cell neoplasms.
  • Accurate classification relies on understanding the specific characteristics of each entity.
  • This review consolidates key information for understanding these lymphomas.