[The treatment of burn wounds with silver sulfadiazine]

Results of clinical and bacteriologic studies of the preparation dermazin, produce of LEC, Ljubljana, Yugoslavia are reported. Dermazin is a 1 percent silver sulphadiazin creme. It has very good antiseptic qualities which allow to maintain for a long time a low count of bacterial colonization in a burn wound. This furnishes opportunity for performing necrectomies. A disadvantage of the cream is its moistening effect on necroses, which renders difficult their removal by chemical necrolytic agents. In comparison with the 0.5 percent silver nitrate solution used so far, dermazin has the following advantages penetrates better in the wound; more convenient form for local application; better tolerated by patients; does not stain skin and bedspread; causes no electrolyte disturbances; has strong bactericidal effect against most common gram-positive and gram-negative bacteria.