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Updated: Jun 28, 2026

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
Published on: February 16, 2022
Flow-injection chemiluminescence determination of chloroquine using peroxynitrous acid as oxidant
Yao-Dong Liang1, Jun-Feng Song, Xiao-Feng Yang
1Institute of Analytical Science, Northwest University, Xi'an 710069, PR China.
Abstract:
A new flow-injection chemiluminescence (CL) method for determination of chloroquine is proposed based on a stronger chemiluminescence of chloroquine in hydrogen peroxide-nitrite-sulfuric acid medium. The proposed method allows the measurement of chloroquine over the range of 3.0x10(-7) to 1.0x10(-5)moll(-1). The detection limit is 8.6x10(-8)moll(-1), and the relative standard deviation for 1.0x10(-6)moll(-1) chloroquine (n=11) is 1.6%. The CL mechanism is also discussed.
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