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Updated: Jun 28, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
[Diagnosis of persistent left superior vena cava in a child using transesophageal echocardiography]
Yuki Toyama1, Takayuki Kunisawa, Michio Nagashima
1Department of Anesthesiology and Critical Care Medicine, Asahikawa Medical College, Asahikawa 078-8510.
Insights
A pediatric patient with X-linked alpha-thalassaemia experienced incorrect central venous (CV) catheter placement. Transesophageal echocardiography (TEE) diagnosed a persistent left superior vena cava (PLSVC), highlighting TEE
Area of Science:
- Pediatric Cardiology
- Medical Imaging
- Vascular Anatomy
Background:
- Central venous catheterization is a common procedure in pediatric patients.
- Anatomical variations can complicate central venous catheter placement.
- X-linked alpha-thalassaemia with mental retardation syndrome presents unique clinical challenges.
Observation:
- A central venous catheter inserted via the left subclavian vein malpositioned towards the left heart.
- Transesophageal echocardiography revealed coronary sinus thickening, indicative of a potential anomaly.
- Contrast echocardiography demonstrated microbubbles flowing from the coronary sinus into the right atrium.
Findings:
- The diagnostic findings confirmed the presence of a persistent left superior vena cava (PLSVC).
- The malpositioned catheter served as an indicator for further investigation.
- Transesophageal echocardiography proved effective in diagnosing PLSVC in this pediatric case.
Implications:
- TEE is a valuable tool for diagnosing persistent left superior vena cava (PLSVC) in pediatric patients with incorrect central venous catheter placement.
- Recognition of anatomical variations like PLSVC is crucial for safe and effective central venous catheterization.
- This case underscores the importance of advanced imaging in pediatric interventional procedures.
Abstract:
An 11-year-old boy with X-linked alpha-thalassaemia/ mental retardation symptom underwent gastrostomy. After the surgical procedure, insertion of a central venous (CV) catheter via the left subclavian vein was performed under X-ray radioscopy. However, the catheter did not move toward the right side of the heart shadow but descended caudally through the left side of the heart shadow. Transesophageal echocardiography (TEE) showed thickening of the coronary sinus, suggesting the existence of a persistent left superior vena cava (PLSVC). Contrast echocardiography using infusion of agitated saline into the CV catheter was performed. Microbubbles flowing from the coronary sinus into the right atrium were observed, and a diagnosis of PLSVC was made. TEE is useful for diagnosis of PLSVC when passage of a CV catheter via the left subclavian vein or left internal jugular vein is incorrect in a pediatric patient.
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