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Updated: Jun 28, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
Flavonoids: prospective drug candidates
Luisa Helena Cazarolli1, Leila Zanatta, Elga Heloisa Alberton
1Departamento de Bioquímica, Centro de Ciências Biológicas, Campus Universitário, UFSC, Bairro Trindade, Cx. Postal 5069, CEP: 88040-970, Florianópolis, SC, Brazil.
Abstract:
The purpose of this review is to discuss the recent developments related to the chemistry and medicinal properties of flavonoids. Major flavonoids that show well categorized structures and well defined structure function-relationships are: flavans, flavanones, flavones, flavanonols, flavonols, catechins, anthocyanidins and isoflavone. The biological properties of flavonoids include antioxidant, anti-inflamatory, antitumoral, antiviral and antibacterial, as well as a direct cytoprotective effect on coronary and vascular systems, the pancreas and the liver. These characteristics place them among the most attractive natural substances available to enrich the current therapy options.
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