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Updated: Jun 28, 2026

Super-resolution Imaging of the Cytokinetic Z Ring in Live Bacteria Using Fast 3D-Structured Illumination Microscopy (f3D-SIM)
Published on: September 29, 2014
Origin of contractile force during cell division of bacteria
1Physics Department, Indian Institute of Technology-Bombay, Powai, Mumbai, India.
Abstract:
When a bacterium divides, its cell wall at the division site grows radially inward like the shutter of a camera and guillotines the cell into two halves. The wall is pulled upon from inside by a polymeric ring, which itself shrinks in radius. The ring is made of an intracellular protein FtsZ (filamenting temperature sensitive Z) and thus is called the Z ring. It is not understood how the Z ring generates the required contractile force. We propose a theoretical model and simulate it to show how the natural curvature of the FtsZ filaments and lateral attraction among them may facilitate force generation.
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