Related Experiment Video
Updated: Jun 28, 2026

Functional Imaging of Auditory Cortex in Adult Cats using High-field fMRI
Published on: February 19, 2014
Discrimination of auditory stimuli during isoflurane anesthesia
Manuel J Rojas1, Jinna A Navas, Stephen A Greene
1Department of Veterinary and Comparative Anatomy, Physiology, and Pharmacology, Washington State University, Pullman, USA.
Abstract:
Deep isoflurane anesthesia initiates a burst suppression pattern in which high-amplitude bursts are preceded by periods of nearly silent electroencephalogram. The burst suppression ratio (BSR) is the percentage of suppression (silent electroencephalogram) during the burst suppression pattern and is one parameter used to assess anesthesia depth. We investigated cortical burst activity in rats in response to different auditory stimuli presented during the burst suppression state. We noted a rapid appearance of bursts and a significant decrease in the BSR during stimulation. The BSR changes were distinctive for the different stimuli applied, and the BSR decreased significantly more when stimulated with a voice familiar to the rat as compared with an unfamiliar voice. These results show that the cortex can show differential sensory responses during deep isoflurane anesthesia.
More Related Videos
08:49Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention
Published on: October 16, 2013
10:50Behavioral Determination of Stimulus Pair Discrimination of Auditory Acoustic and Electrical Stimuli Using a Classical Conditioning and Heart-rate Approach
Published on: June 6, 2012
Related Concept Videos
Inhalational Anesthetics: Overview
Stages of General Anesthesia
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...