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Related Concept Videos

Gastric Emptying01:16

Gastric Emptying

Gastric emptying occurs when the stomach gradually releases chyme into the duodenum. When the stomach is distended, it triggers the release of gastrin, a hormone that promotes gastric acid secretion to aid in digestion. Additionally, stomach distension contributes to peristaltic waves that propel gastric contents toward the pyloric region. The gastroenteric reflex, on the other hand, primarily stimulates peristalsis in the intestines, facilitating the movement of contents further along the...
Bioavailability Study Design: Healthy Subjects Versus Patients01:15

Bioavailability Study Design: Healthy Subjects Versus Patients

Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
One-Compartment Open Model for IV Bolus Administration: General Considerations01:19

One-Compartment Open Model for IV Bolus Administration: General Considerations

The one-compartment model is a pharmacokinetic tool that models the body as a single, uniform compartment, facilitating the understanding of drug distribution and elimination. This model is particularly beneficial for intravenous (IV) bolus administration, where the drug rapidly circulates throughout the body.
The drug's presence in the body is defined by an equation representing the difference between the rates of drug entry and exit. Key parameters—elimination rate constant, half-life,...
Upper GI Series: Barium Swallow01:24

Upper GI Series: Barium Swallow

The Barium Swallow Study, or a Barium Esophagogram, is a diagnostic imaging method used to visualize the upper gastrointestinal (GI) tract, including the esophagus, stomach, and small intestine. It employs barium sulfate, a radiopaque contrast material, to provide clear images of the upper digestive system, helping to identify abnormalities, diseases, or structural issues.
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Patients undergoing this procedure ingest a liquid containing barium sulfate with a chalky...
Bioavailability Study Design: Single Versus Multiple Dose Studies01:11

Bioavailability Study Design: Single Versus Multiple Dose Studies

Bioavailability studies are essential for understanding how a drug is absorbed, distributed, metabolized, and excreted in the body. These studies assess the extent and rate at which the active pharmaceutical agent becomes available at the site of action. The design of bioavailability studies can involve single-dose or multiple-dose regimens, each with distinct advantages and limitations.Single-dose studies are the preferred approach due to their simplicity and reduced drug exposure for...

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Updated: Jun 28, 2026

Gastric Point of Care Ultrasound in Adults: Image Acquisition and Interpretation
05:50

Gastric Point of Care Ultrasound in Adults: Image Acquisition and Interpretation

Published on: September 22, 2023

The gastric emptying study: protocol design considerations.

William C Klingensmith1, Steven P Lawrence

  • 1Department of Radiology, Porter Hospital, Denver, Colorado, USA. bill.klingensmith@mac.com

Journal of Nuclear Medicine Technology
|November 15, 2008
PubMed
Summary
This summary is machine-generated.

Instant oatmeal and scrambled eggs provide similar gastric emptying information. Frequent stomach-colon overlap in CT imaging may complicate delayed scans, while LAO projection offers better jejunum visualization.

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Area of Science:

  • Gastroenterology
  • Nuclear Medicine
  • Radiology

Background:

  • Gastric emptying studies are crucial for diagnosing gastrointestinal motility disorders.
  • Standardized meal compositions and imaging techniques are essential for reliable results.
  • Understanding anatomical overlap in imaging projections is key for accurate interpretation.

Purpose of the Study:

  • To assess the intrapatient correlation of gastric emptying times using instant oatmeal and scrambled egg meals.
  • To evaluate the degree of stomach-colon and stomach-jejunum overlap in anterior-posterior (AP) and left anterior oblique (LAO) CT projections.

Main Methods:

  • 15 patients underwent two gastric emptying studies (oatmeal and egg meals labeled with 99mTc-sulfur colloid) 1 day apart.
  • Upright LAO projection imaging with 1-minute digital images every 15 minutes to calculate half-time of emptying.
  • 100 abdominal CT studies were analyzed for stomach-colon/jejunum overlap in AP and LAO projections, categorized as none, mild, moderate, or marked.

Main Results:

  • A significant correlation (r=0.77, P<0.01) was found between gastric emptying half-times for oatmeal and egg meals in 14 patients.
  • Stomach-colon overlap occurred in 74% (AP) and 82% (LAO) of CT studies.
  • Stomach-jejunum overlap was frequent (77% AP, 52% LAO), with less overlap in the LAO projection (P<0.05).

Conclusions:

  • Instant oatmeal and scrambled eggs are comparable for assessing gastric emptying.
  • Frequent stomach-colon overlap in CT imaging may interfere with delayed scans due to colonic activity.
  • The LAO projection may be advantageous for gastric emptying studies due to reduced stomach-jejunum overlap, aiding lag time calculations.