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Laparoscopic Cholecystectomy with Indocyanine Green Fluorescence: Choledochoscopic Stone Extraction and Primary Duct Suture
Published on: November 25, 2025
Transgastric cholecystectomy using a prototype endoscope with 2 deflecting working channels (with video)
J Andres Astudillo1, Emanuel Sporn, Sharon Bachman
1Department of Surgery, University of Missouri-Columbia, Columbia, Missouri 65212, USA. andyastudillo@hotmail.com
A novel prototype endoscope with dual deflecting channels enabled successful transgastric cholecystectomy in pigs. This instrument shows promise for improving minimally invasive gallbladder removal procedures in humans.
Area of Science:
- Minimally Invasive Surgery
- Gastroenterology
- Surgical Instrumentation
Background:
- Transgastric cholecystectomy (gallbladder removal) is feasible but technically challenging with current instruments.
- Existing instrumentation limits the practicality of transgastric approaches.
Purpose of the Study:
- To evaluate a prototype endoscope designed for transgastric cholecystectomy.
- The endoscope features two working channels with distal tip deflectors.
Main Methods:
- A study involving sixteen male pigs (six nonsurvival, ten survival).
- Transgastric cholecystectomy was performed using a dual-channel Olympus endoscope with deflecting channels.
- Gallbladder retraction was assisted by a laparoscopic grasper.
Main Results:
- Successful cholecystectomy was achieved in all ten survival pigs.
- Median procedure time was 81 minutes, decreasing with experience.
- Excellent visualization, successful clipping of cystic duct/artery, and enhanced dissection were noted.
- Nine of ten animals survived without complications; one died from peritonitis.
Conclusions:
- The prototype endoscope with deflecting working channels facilitates transgastric cholecystectomy in pigs.
- The endoscope proved stable, eliminating the need for an overtube and aiding retraction/dissection.
- This technology holds significant promise for human transgastric cholecystectomy procedures.
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