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Updated: Jun 27, 2026

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A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects
Published on: May 4, 2021
Inhaled nitric oxide and neuroprotection in preterm infants
Jeremy D Marks1, Michael D Schreiber
1Department of Pediatrics, University of Chicago, Chicago, IL 60637, USA. jmarks@uchicago.edu
Clinics in Perinatology
|November 26, 2008
Abstract:
Although inhaled nitric oxide-mediated decreases in chronic lung disease and severe intraventricular hemorrhage/periventricular leukomalacia undoubtedly contribute to improved neurodevelopmental outcomes, inhaled nitric oxide has an independent neuroprotective effect. Although these data are encouraging, additional studies are required before recommending the routine use of inhaled nitric oxide for neuroprotection in preterm infants.

