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Updated: Jun 27, 2026

Surgical Approach, Challenges, and Resolutions for Uterus Transplantation in Rats
Published on: April 14, 2023
[Uterine transplantation: animal and human studies]
T Gauthier1, S Hardeman, P Piver
1Service de gynécologie-obstétrique, hôpital de la Mère et de l'Enfant, CHU de Limoges, 8, avenue Dominique-Larrey, 87000 Limoges, France. gauthiertristan@yahoo.fr
Abstract:
Many cases of not life saving transplanted organs were described with the aim of improving quality of life. Uterus graft could be an alternative solution to adoption or surrogacy for women who have uterine factor infertility. Different animals' studies with mouse, sheep or monkey showed feasibility of the surgical technique with large vessels patch. One case of human uterine transplant has been reported but failed. Cold storage of the uterus in protective solution has been explored with mouse, sheep and human. Only pregnancy after uterus graft by syngenic mouse has been published. Results about pregnancy after allograft with sheep or monkey are necessary before pregnancy after human uterus graft becomes a reality.
