A liposomal delivery vehicle for the anticancer agent gossypol
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Published on: April 26, 2016
Guangxi Zhai1, Jun Wu, Xiaobin Zhao
1College of Pharmacy, Shandong University, Jinan 250012, P. R. China.
Background:
Gossypol has recently been identified as a potential anticancer agent. In this study, a novel liposomal formulation is evaluated for delivery of gossypol.
Materials And Methods:
Gossypol was incorporated into liposomes. The liposomes were characterized for physical and chemical properties and for in vitro cytotoxicity.
Results:
Gossypol was stably encapsulated in these liposomes and exhibited cytotoxicity towards cancer cells.
Conclusion:
Liposomes can be used effectively as gossypol carriers.
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