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Evaluation for concomitant thyroid nodules and primary hyperparathyroidism in patients undergoing parathyroidectomy
Shane Y Morita1, Helina Somervell, Christopher B Umbricht
1Endocrine Surgery Section, Department of Surgery, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Surgery
|December 2, 2008
Summary
Thyroid nodules frequently coexist with primary hyperparathyroidism. Preoperative screening for both conditions in patients undergoing thyroidectomy or parathyroidectomy can detect concurrent diseases, including thyroid cancer.
Area of Science:
- Endocrine Surgery
- Surgical Oncology
Background:
- Thyroid nodules and primary hyperparathyroidism are known to coexist.
- Previous studies have reported on the incidence of one condition in patients with the other.
Purpose of the Study:
- To determine the incidence of concomitant thyroid nodular disease and primary hyperparathyroidism in patients undergoing parathyroidectomy or thyroidectomy at a single center.
Main Methods:
- A retrospective review of 526 patients who underwent thyroidectomy, parathyroidectomy, or both between May 2006 and December 2007.
- Preoperative screening for concomitant thyroid nodular disease or primary hyperparathyroidism was performed.
Main Results:
- Among 200 patients undergoing parathyroidectomy, 51.0% had thyroid nodular disease, with 6% having thyroid malignancy.
- In 326 patients primarily treated for thyroid disease, the incidence of primary hyperparathyroidism was 3.1%.
Conclusions:
- A comprehensive preoperative approach can identify concomitant thyroid disease and primary hyperparathyroidism.
- This strategy aids in detecting unsuspected thyroid cancer and hyperparathyroidism, preventing reoperative surgeries.
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