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Related Concept Videos

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...

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Related Experiment Video

Updated: Jun 27, 2026

Du-Moxibustion in a Mouse Model of Ankylosing Spondylitis
04:47

Du-Moxibustion in a Mouse Model of Ankylosing Spondylitis

Published on: October 27, 2023

[Ankylosing Spondylitis].

Hiroshi Mitsui1

  • 1Mitsui Hiroshi CLINIC.

Clinical Calcium
|December 2, 2008
PubMed
Summary

Ankylosing Spondylitis (AS) is a rheumatoid disease with distinct clinical features. Early diagnosis and treatment are crucial for managing AS and its related symptoms effectively.

Area of Science:

  • Rheumatology
  • Immunology
  • Clinical Medicine

Context:

  • Ankylosing Spondylitis (AS) is a significant rheumatoid disease with unique clinical manifestations.
  • Accurate diagnosis is paramount for effective management of AS.
  • AS is increasingly recognized within the spectrum of seronegative spondylarthropathies (SPA).

Purpose:

  • To detail new modified diagnostic criteria for Ankylosing Spondylitis.
  • To present differential diagnoses aiding in AS identification.
  • To highlight characteristic clinical features of AS and SPA.

Summary:

  • This work details updated diagnostic criteria for Ankylosing Spondylitis (AS), a rheumatoid disease.
  • It emphasizes the importance of differential diagnosis and characteristic symptoms like spinal, ocular, skin, and systemic lesions, and enthesopathy.

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Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
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Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

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Last Updated: Jun 27, 2026

Du-Moxibustion in a Mouse Model of Ankylosing Spondylitis
04:47

Du-Moxibustion in a Mouse Model of Ankylosing Spondylitis

Published on: October 27, 2023

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
06:23

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

  • AS is positioned centrally within seronegative spondylarthropathies (SPA) due to shared symptoms.

    • Impact:

    • Facilitates earlier and more accurate diagnosis of Ankylosing Spondylitis.
    • Improves understanding of AS within the broader category of seronegative spondylarthropathies.
    • Underscores the critical link between timely diagnosis and effective treatment outcomes for AS patients.