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Updated: Jun 27, 2026
A Facile and Eco-friendly Route to Fabricate Poly(Lactic Acid) Scaffolds with Graded Pore Size
Published on: October 17, 2016
Surface engineering of poly(D,L-lactic acid) by entrapment of soluble eggshell membrane protein
Jian-Wei Lu1, Qiang Li, Qing-Lei Qi
1Department of Chemical Engineering, Institute of Polymer Science and Engineering, School of Materials Science and Engineering, Tsinghua University, Beijing 100084, People's Republic of China.
Abstract:
Soluble eggshell membrane protein (SEP) is used to engineer poly(D,L-lactic acid) (PDL-LA) membrane surface by a physical entrapment method to enhance cytocompatibility. Attenuated total reflection Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, and contact angle measurements are used to characterize SEP-modified PDL-LA membrane surface and confirm the formation of an even and stable layer of SEP on PDL-LA membrane surface. NIH3T3 cell lines are used as model cells to evaluate cytocompatibility of the SEP-modified PDL-LA membrane, which is much better than that of virgin PDL-LA membrane. The enhanced cytocompatibility facilitates potential application in tissue engineering.
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