Seminoma: a review of 15 years experience

We retrospectively reviewed the Charleston Area Medical Center (CAMC) experience with 54 patients diagnosed with seminoma between 1970 and 1986. The median age at diagnosis was 37.5 years (range 20-79). The highest percentage of seminomas occurred between the ages of 30 and 39 (50 percent). Treatment was primarily orchiectomy and radiotherapy since most patients presented with localized disease. The five year survival rate was 100 percent for stage I, 86 percent for stage II, and 75 percent for stage III. Sixteen of 18 (89 percent) stage I patients survived at least 10 years. Of the 12 patients who died, two (16 percent) died of recurrent seminoma, six of cardiovascular disease, and four of a second primary malignancy. The excellent five and 10-year survival rates in stage I seminoma treated with surgery and radiotherapy in this series is similar to others.