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Anaphylactic-like reaction to lugol solution during colposcopy.
Ugo Indraccolo1, Katia Palombino, Pantaleo Greco
1Department of Surgical Sciences, Institute of Obstetrics and Gynecology, University of Foggia, Foggia, Puglia, Italy. ugo.indraccolo@libero.it
Southern Medical Journal
|December 17, 2008
Summary
Lugol iodine solution used in the Schiller test during colposcopy can cause severe anaphylactic-like reactions. Prompt saline washout resolved symptoms, highlighting the need to assess the safety of this common diagnostic staining procedure.
Area of Science:
- Gynecology
- Colposcopy
- Diagnostic Procedures
Background:
- The Schiller test utilizes Lugol iodine solution to stain genital epithelia during colposcopy.
- Adverse effects of Lugol iodine staining in this context are not well-documented.
Observation:
- A patient experienced an anaphylactic-like reaction during a Schiller test.
- Symptoms included vaginal and generalized pruritus, edema, hypotension, tachycardia, and respiratory distress.
Findings:
- The patient's symptoms resolved completely after vaginal iodine washout with saline.
- No pharmacological interventions were required for symptom resolution.
Implications:
- The safety profile of Lugol iodine staining during colposcopy requires further investigation.
- Clinicians should be aware of potential severe adverse reactions to Lugol solution.
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