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Updated: Jun 27, 2026

Novel Surgical Rodent Model for Studying Neuroma Pain Treatment Options using Targeted Muscle Reinnervation Through the Saphenous Nerve
Published on: November 14, 2025
Medial sural cutaneous nerve biopsy
James Fallon Thornton1, Jason Wang, Christopher Jerron Riley
1*Department of Plastic Surgery daggerSouthwestern Medical School double daggerSTARS Summer Research Program for Students, University of Texas Southwestern Medical Center at Dallas, Dallas, TX.
Abstract:
This paper describes indications, preoperative preparation, operative technique, and postoperative care for an adaptation of a commonly performed, outpatient neurology procedure, the sural nerve biopsy. We performed a chart review on 12 patients, with follow-ups ranging from 6 to 26 months, treated by the PI (J.F.T.) over 3 years, and only 1 noted complication (delayed wound healing in a steroid-dependent person). All procedures were performed in an operating room setting under local anesthetic with standby intravenous sedation. We provide a stepwise procedure description of this technique that can be performed with very low morbidity in an outpatient, minor procedure setting.

