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k-TE generalized autocalibrating partially parallel acquisition (GRAPPA) for accelerated multiple gradient-recalled
Xiaoming Yin1, Andrew C Larson
1Department of Radiology, Northwestern University, Chicago, Illinois 60611, USA.
Magnetic Resonance in Medicine
|December 20, 2008
Summary
Accelerating abdominal R(2)* mapping with k-echo time (k-TE) GRAPPA significantly reduces artifacts and improves accuracy. This new method enhances Magnetic Resonance Imaging (MRI) by shortening scan times for R(2)* measurements.
Area of Science:
- Medical Imaging
- Magnetic Resonance Imaging (MRI)
- Quantitative MRI
Background:
- Multiple gradient-recalled echo (MGRE) is standard for abdominal R(2)* mapping.
- Accelerated acquisitions can improve spatial resolution and reduce breath-hold times.
Purpose of the Study:
- To compare acceleration methods for MGRE abdominal R(2)* mapping.
- To evaluate view-sharing (VS), GRAPPA, and k-TE GRAPPA.
- To assess artifact reduction and measurement accuracy.
Main Methods:
- Phantom and volunteer studies were conducted.
- Compared VS, GRAPPA, and k-TE GRAPPA for MGRE acceleration.
- Utilized water-selective spatial spectral excitation pulses.
Main Results:
- k-TE GRAPPA and VS methods benefited from water-selective pulses.
- VS methods showed sensitivity to off-resonance effects at higher acceleration.
- k-TE GRAPPA reduced artifacts and improved accuracy compared to GRAPPA.
Conclusions:
- k-TE GRAPPA effectively reduces scan times for abdominal R(2)* mapping.
- This method offers a promising approach for accelerated quantitative MRI.
- Further validation of k-TE GRAPPA in clinical settings is warranted.

