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Related Concept Videos

Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
Gastritis II: Pathophysiology01:26

Gastritis II: Pathophysiology

The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...
Gastritis-I: Introduction and Types01:27

Gastritis-I: Introduction and Types

Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...

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Chronic Salmonella Infection Induced Intestinal Fibrosis
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Chronic Salmonella Infection Induced Intestinal Fibrosis

Published on: September 22, 2019

Collagenous gastritis.

Richa Jain1, Runjan Chetty

  • 1Department of Pathology, University Health Network, University of Toronto, Ontario, Canada.

International Journal of Surgical Pathology
|December 24, 2008
PubMed
Summary
This summary is machine-generated.

Collagenous gastritis, a rare condition, can affect young patients and present with stomach pain. Diagnosis involves identifying a collagenous subepithelial band on gastric biopsy, sometimes alongside Helicobacter pylori infection.

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Area of Science:

  • Gastroenterology
  • Pathology

Background:

  • Collagenous gastritis is a rare gastrointestinal disorder characterized by excessive collagen deposition in the gastric subepithelium.
  • While often associated with watery diarrhea syndrome, it can present in isolation within the stomach.

Observation:

  • A 25-year-old patient presented with epigastric pain.
  • Gastric biopsy revealed a prominent subepithelial collagenous band, confirmed by Masson's trichrome staining.
  • The patient had coexisting Helicobacter pylori gastritis but no lymphocytic gastritis or watery diarrhea.

Findings:

  • The case demonstrates that collagenous gastritis can occur in young individuals.
  • The condition may be confined to the stomach without concurrent systemic symptoms like watery diarrhea.
  • Helicobacter pylori gastritis was noted as a potential associated factor.

Implications:

  • This case highlights the importance of considering collagenous gastritis in young patients with unexplained epigastric pain.
  • It underscores that collagenous gastritis can be a stomach-limited disease, potentially unrelated to celiac disease or watery diarrhea syndrome.
  • Further research may elucidate the specific role of Helicobacter pylori in the pathogenesis of gastric collagen deposition.