Related Experiment Video
Updated: Jun 26, 2026

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale
Published on: July 8, 2025
Pattern of pediatric zolpidem ingestions reported to Texas poison control centers, 2000 to 2006
1Epidemiology and Disease Surveillance Unit, Texas Department of State Health Services, 1100 W 49th St, Austin, TX 78756, USA. mathias.forrester@dshs.state.tx.us
Insights
Young children ingesting zolpidem (a sleep aid) typically experience minor effects and can often be managed at home. This study analyzed unintentional zolpidem exposures reported to poison control centers.
Area of Science:
- Toxicology
- Pediatric Medicine
- Public Health
Background:
- Zolpidem is a commonly prescribed sedative-hypnotic medication.
- Accidental pediatric ingestions of medications pose a significant public health concern.
- Understanding ingestion patterns is crucial for prevention and management strategies.
Purpose of the Study:
- To characterize the patterns of zolpidem ingestions in young children.
- To analyze demographic and clinical factors associated with zolpidem ingestions.
- To determine the medical outcomes of pediatric zolpidem exposures.
Main Methods:
- Retrospective analysis of zolpidem ingestions in children aged 0-5 years.
- Data collected from Texas poison control centers between 2000-2006.
- Exclusion of multiple substance ingestions; analysis of patient demographics, ingestion circumstances, management, and outcomes.
Main Results:
- A total of 463 unintentional zolpidem ingestions were reported.
- Most ingestions (92.8%) occurred in the child's home.
- The majority of cases resulted in no (59.0%) or minor (35.1%) effects, with on-site management in 54.4% of cases.
Conclusions:
- Pediatric zolpidem ingestions, when isolated, rarely lead to severe outcomes.
- Home management is frequently appropriate for unintentional pediatric zolpidem exposures.
- Findings underscore the importance of safe medication storage to prevent childhood poisonings.
Objectives:
The purpose of this study was to describe the pattern of zolpidem ingestions by young children reported to poison control centers.
Methods:
Cases were all zolpidem ingestions by children 0 to 5 year old reported to Texas poison control centers during 2000 to 2006. Multiple substance ingestions were excluded. The distribution of cases was described with respect to such demographic and clinical factors as patient gender, ingestion reason, ingestion site, management site, and medical outcome.
Results:
There were a total of 463 cases, all unintentional exposures. The patient was male in 52.2% of the cases, and the exposure occurred at the patient's own home in 92.8% of the cases. The patient was managed on-site in 54.4% cases, already at or en route to a health care facility in 29.6% cases, and referred to a health care facility in 16.0% cases. Of the 322 cases with a known final medical outcome, 59.0% had no effect, 35.1% had minor effects, and 5.9% had moderate effects.
Conclusions:
Pediatric ingestions of zolpidem alone reported to Texas poison control centers most frequently resulted in at most minor effects and were often managed at home.
Related Concept Videos
Pharmaceutical Poisoning: Potential Scenarios
Toxidromes: Clinical Features
Drug Toxicity: Risk factors
Pharmaceutical Poisoning: Treatment Strategies
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Pharmacokinetics in Pediatric Patients: Drug Excretion
