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Published on: September 22, 2023
[Expression of SleX in nasal epithelium with chronic rhinosinusitis]
Xuewei Zhu1, Dongdong Zhu, Kewei Sun
1Department of Otolaryngology Head and Neck Surgery, China-Japan Union Hospital, Jilin University, Changchun, 130033, China.
Objective:
To explore the expression of SleX in nasal epithelium in patients with chronic rhinosinusitis.
Method:
Nine nasal epitheliums from patients with chronic rhinosinusitis and 7 normal controls were stained with SleX antibody by immunohistochemistry, and its expression were analyzed.
Result:
Both nasal epithelial cells and neutrophils expressed SleX. Nearly 88.9% nasal epithelium from patients with chronic rhinosinusitis expressed SleX while 14.3% in normal control. Expression of SleX in nasal epitheliums from patients with chronic rhinosinusitis were higher than that in normal control. There were significant difference between two groups.
Conclusion:
Nasal epithelium from patients with CRS is highly expressed SleX. It may involve the occurrence of chronic rhinosinusitis.
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