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Updated: Jun 26, 2026

A Unified Methodological Framework for Vestibular Schwannoma Research
Published on: June 20, 2017
Hearing preservation in vestibular schwannoma stereotactic radiosurgery: what really matters?
1Department of Neurological Surgery, University of California, Irvine Medical Center, Orange, California 92868, USA. mlinskey@uci.edu
Abstract:
Stereotactic radiosurgery (SRS) for vestibular schwannomas has evolved and improved over time. Although early short-term follow-up reports suggest that fractionation yields hearing preservation rates equivalent to modern single-dose SRS techniques, significant questions remain regarding long-term tumor control after the use of fractionation in a late responding tumor with a low proliferative index and alpha/beta ratio. With single-dose SRS, critical hearing preservation variables include: 1) strict attention to prescription dose 3D conformality so that the ventral cochlear nucleus (VCN) receives