Related Experiment Video
Updated: Jun 26, 2026
08:51
A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
Decrease in total aneurysm-related deaths in the era of endovascular aneurysm repair.
Kristina A Giles1, Frank Pomposelli, Allen Hamdan
1Beth Israel Deaconess Medical Center, Boston, Mass. 02215, USA.
Journal of Vascular Surgery
|January 13, 2009
Summary
Endovascular aneurysm repair (EVAR) has significantly reduced deaths from abdominal aortic aneurysms (AAA). Despite increased AAA repair volume, mortality rates for both intact and ruptured AAA decreased post-EVAR introduction.
Area of Science:
- Vascular Surgery
- Public Health
- Medical Technology Assessment
Background:
- The introduction of endovascular aneurysm repair (EVAR) for abdominal aortic aneurysms (AAA) raised concerns about potential increases in aneurysm-related deaths despite lower operative mortality.
- Evaluating national trends in AAA repair volume and mortality rates before and after EVAR's introduction is crucial.
Purpose of the Study:
- To assess the impact of endovascular aneurysm repair (EVAR) on abdominal aortic aneurysm (AAA) repair volumes and mortality rates.
- To compare outcomes for intact and ruptured AAA repair in the pre-EVAR and post-EVAR eras.
Main Methods:
- Utilized the Nationwide Inpatient Sample database (1993-2005) to identify patients with intact or ruptured AAA undergoing open repair or EVAR.
- Analyzed annual trends in AAA repair numbers, ruptured AAA diagnoses without repair, deaths, and mortality rates.
- Compared outcomes between the pre-EVAR (1993-1998) and post-EVAR (2001-2005) periods.
Main Results:
- EVAR adoption increased, accounting for 56% of repairs by 2005, with significantly lower mortality (1.3%) compared to open repair.
- Mean annual intact AAA repairs increased, while deaths and mortality rates significantly decreased post-EVAR (4.0% to 3.1%).
- Ruptured AAA repair volume and deaths decreased significantly, with reduced mortality rates for both open repair and EVAR.
Conclusions:
- The introduction of EVAR has led to a significant decrease in annual deaths from both intact and ruptured abdominal aortic aneurysms.
- EVAR adoption coincided with increased intact AAA repair and decreased ruptured AAA diagnoses and repair volumes.
- EVAR has demonstrably improved survival outcomes for abdominal aortic aneurysm patients.
Related Concept Videos
01:26Aneurysm III: Interprofessional Care
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
01:22Aneurysm IV: Nursing Management
Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...