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Published on: October 25, 2017
Isolation of Salmonella paratyphi A from renal abscess
Sanjay D'Cruz1, Suman Kochhar, Sandeep Chauhan
1Department of Medicine, Government Medical College and Hospital, Sector 32, Chandigarh - 160 030, UT Chandigarh, India. sanjaydcruz@gmail.com
Abstract:
Intrarenal abscesses remain a significant cause of morbidity and mortality as well as a diagnostic dilemma because a plethora of microorganisms can cause this condition. A definitive diagnosis is made by demonstrating the organisms from the aspirate and the success or failure of therapy depends upon the antimicrobial sensitivity pattern. Enteric fever is a multisystem disorder caused by invasive strains of salmonella. Salmonellosis continues to be a major public health problem, especially in developing countries. Classic enteric fever is caused by S. typhi and usually less severe enteric fevers are caused by S. paratyphi A, B, or C. However, at times S. paratyphi is capable of causing serious and often life-threatening infections like infective endocarditis, pericarditis, empyma, sino-venous thrombosis, osteomyelitis, meningitis, bone marrow infiltration, hepatitis and pancreatitis. There are anecdotal case reports in world literature of abscesses being caused by this organism. Renal involvement like bacteriuria, nephrotic syndrome and acute renal failure have been reported due to S. parayphi A. S. paratyphi A has never been implicated in renal abscess, we report one such case that was managed successfully with medical therapy.
Insights
Salmonella Paratyphi A, a cause of enteric fever, can lead to serious infections. This report details the first case of an intrarenal abscess caused by Salmonella Paratyphi A, successfully treated with antibiotics.
Area of Science:
- Infectious Diseases
- Nephrology
- Microbiology
Background:
- Intrarenal abscesses are serious infections with diverse microbial causes, posing diagnostic challenges.
- Enteric fever, caused by invasive Salmonella strains, is a significant global health issue, particularly in developing nations.
- Salmonella Paratyphi A is known to cause various severe infections, but not previously intrarenal abscesses.
Observation:
- A case of intrarenal abscess caused by Salmonella Paratyphi A is presented.
- This represents the first documented instance of Salmonella Paratyphi A implicated in renal abscess formation.
- The patient's condition was successfully managed with antimicrobial therapy.
Findings:
- Salmonella Paratyphi A, typically associated with less severe enteric fever, can manifest in severe, life-threatening conditions.
- The study confirms Salmonella Paratyphi A as a causative agent of intrarenal abscess.
- Successful treatment was achieved through medical management, highlighting the importance of antimicrobial sensitivity.
Implications:
- This case expands the spectrum of known complications associated with Salmonella Paratyphi A infections.
- It underscores the need for considering Salmonella Paratyphi A in the differential diagnosis of intrarenal abscesses, even in atypical presentations.
- The findings support the efficacy of medical therapy in managing Salmonella Paratyphi A-induced intrarenal abscesses.
