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Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
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Nine-year routine clinical experience of aortic valve replacement with ATS mechanical valves

Jean-Pierre Villemot1, Malik Lekehal, Pablo Maureira

  • 1Department of Cardiothoracic Surgery and Transplantation, University-Hospital of Nancy-Brabois, Vandoeuvre-lès-Nancy, France. jp.villemot@chu-nancy.fr

The Journal of Heart Valve Disease
|January 14, 2009
PubMed

Insights

The ATS mechanical valve shows good early and long-term outcomes in aortic valve replacement (AVR) patients. Survival rates are favorable, with low rates of complications like thromboembolism and bleeding.

Area of Science:

  • Cardiac Surgery
  • Biomaterials and Medical Devices
  • Cardiovascular Medicine

Background:

  • Aortic valve replacement (AVR) is a critical procedure for managing aortic valve disease.
  • Mechanical prostheses are widely used, with the ATS valve being a common choice.
  • Understanding long-term outcomes is essential for patient selection and management.

Purpose of the Study:

  • To evaluate the early and long-term outcomes of aortic valve replacement (AVR) using the ATS mechanical prosthesis.
  • To assess the performance of the ATS valve in a routine clinical practice setting.
  • To identify factors influencing patient survival and complications after AVR.

Main Methods:

  • Retrospective analysis of clinical data from 510 consecutive patients undergoing AVR with the ATS mechanical prosthesis (1996-2005).
  • Patients included isolated AVR and those with concomitant procedures (CABG, MVP, AAR).
  • Analysis of early and late morbidity/mortality, considering emergency surgery, low ejection fraction, and advanced age.

Main Results:

  • Overall 30-day mortality was 7.2%, with variations based on concomitant procedures.
  • Five- and nine-year survival rates were 81.14% and 67.02%, respectively.
  • Lower long-term survival was observed in emergency cases, low LVEF (<50%), and patients aged ≥70 years. Postoperative valve-related death was 1.1%/pt-yr, with low rates of thromboembolism (0.4%/pt-yr) and bleeding (0.63%/pt-yr). No valve thrombosis, structural dysfunction, or endocarditis were reported.

Conclusions:

  • The ATS mechanical valve demonstrates globally very good performance in AVR.
  • Outcomes are comparable to previously reported results for mechanical valves.
  • The study supports the continued use of the ATS valve in clinical practice.
Abstract

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