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Herbal remedy for diabetes: two case reports
R N Kulambil Padinjakara1, K Ashawesh, S Butt
1Diabetes and Endocrinology Center, University Hospital of Coventry and Warwickshire, Coventry, UK.
Summary
Herbal diabetes medicines from India were found to contain glibenclamide, a modern drug. This adulteration poses risks for type 2 diabetes management.
Area of Science:
- Pharmacology
- Endocrinology
- Public Health
Background:
- Type 2 diabetes management often involves conventional medications.
- Complementary and alternative medicines (CAM) are widely used globally.
- Herbal remedies are a common form of CAM for chronic conditions like diabetes.
Observation:
- Two patients with type 2 diabetes reported using herbal medicines purchased from India.
- These herbal products were marketed for their purported effectiveness in diabetes management.
- Chemical analysis was performed on the herbal medicines consumed by the patients.
Findings:
- The herbal medicines were found to be adulterated with glibenclamide.
- Glibenclamide is a sulfonylurea, a class of oral hypoglycemic agents used in modern diabetes treatment.
- The presence of undeclared pharmaceutical ingredients in herbal products is a significant concern.
Implications:
- Adulteration of herbal medicines with prescription drugs can lead to serious adverse events.
- This poses a critical challenge for healthcare providers managing patients using CAM.
- Increased regulatory oversight and consumer awareness are crucial for ensuring the safety of alternative medicines.
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