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Updated: Jun 26, 2026

Fibroblast-Derived 3D Matrix System Applicable to Endothelial Tube Formation Assay
Published on: December 26, 2019
Biomatrix on the basis of polypropylene mesh and fetal fibroblasts
N V Mal'tseva1, V A Panchenko, E G Prokop'eva
1Novokuznetsk State Institute for Upgrading of Physicians, Ministry of Health of the Russian Federation, Russia. ninamaltseva@nm.ru
Abstract:
A technology for obtaining a biomatrix on the basis of polypropylene mesh, used in clinical surgery, and cultured fetal fibroblasts is proposed. The method was developed on experimental animal cells. It includes culturing of rat fetal fibroblasts on fibers of a polypropylene mesh, treated with wheat germ lectin. This technology can be used for obtaining a biomatrix with fibroblasts of different origin. This biomatrix can be used in experimental and clinical surgery for dressing and stimulation of effective healing of mechanical injuries to the connective tissue.

