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Related Experiment Video

Updated: Jun 26, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

Alternative method for cardiac resynchronization: transapical lead implantation.

Imre Kassai1, Csaba Foldesi, Andrea Szekely

  • 1Gottsegen Gyorgy Hungarian Institute of Cardiology, Budapest, Hungary.

The Annals of Thoracic Surgery
|January 24, 2009
PubMed
Summary

Transapical lead implantation offers a novel, minimally invasive alternative for cardiac resynchronization therapy when standard methods fail. This technique provides effective endocardial pacing without impacting the mitral valve.

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Published on: February 28, 2012

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Medical Device Technology

Background:

  • Cardiac resynchronization therapy (CRT) is crucial for heart failure management.
  • Coronary sinus lead implantation is the standard CRT approach but can fail.
  • Alternative lead placement strategies are needed for CRT when conventional methods are unsuccessful.

Purpose of the Study:

  • To introduce and describe a novel transapical approach for endocardial lead implantation.
  • To evaluate the feasibility of this new technique for cardiac resynchronization therapy.

Main Methods:

  • Utilized direct puncture of the left ventricular apex via the Seldinger technique.
  • Employed standard active fixation endocardial pacing leads.
  • Guided lead tip positioning using intracavitary navigation under fluoroscopy.

Main Results:

  • Successfully demonstrated a fundamentally new approach for lead implantation.
  • The transapical method is minimally invasive.
  • Achieved endocardial pacing without mitral valve involvement.

Conclusions:

  • Transapical lead implantation is a viable alternative for CRT.
  • This technique offers advantages over traditional methods, particularly in cases of lead implantation failure.
  • The approach is minimally invasive and avoids mitral valve complications.