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Updated: Jun 26, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
[Endogenous Clostridium septicum panophthalmitis associated with gastrointestinal malignancy]
Michala Kehrer1, Michael Kjeldgaard, Sanne Kjaer Hansen
1Infektionsmedicinsk afdeling, Odense Universitetshospital, Sdr. Boulevard 29, DK-5000 Odense C. Michala@mail.dk
Abstract:
Endogenous panophthalmitis due to Clostridium septicum (C. septicum) is a rare, but life-threatening condition. There is a known association between infection and malignancy. Our patient presented with panophthalmitis - with visual loss, proptosis, raised intraocular pressure and air bubble in the anterior chamber. C. septicum was found in cultures of pus. He was treated with antibiotics and surgery, and recovered. Further investigations showed carcinoma of the colon. This case stresses the need for urgent treatment and subsequent investigation for occult malignancy.
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