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Updated: Jun 26, 2026

Simultaneous Electrocardiography Recording and Invasive Blood Pressure Measurement in Rats
Published on: January 31, 2019
Nexfin noninvasive continuous blood pressure validated against Riva-Rocci/Korotkoff.
Daan W Eeftinck Schattenkerk1, Johannes J van Lieshout, Anton H van den Meiracker
1Special Medical Care, Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
The Nexfin monitor accurately measures blood pressure (BP) continuously and noninvasively. Its precision in continuous noninvasive arterial pressure (NAP) monitoring is comparable to traditional auscultatory methods (RRK).
Area of Science:
- Cardiovascular physiology
- Biomedical engineering
- Medical device technology
Background:
- Continuous blood pressure (BP) monitoring is crucial for patient care.
- The Finapres methodology enables noninvasive BP measurement.
- The Nexfin monitor represents the latest advancement in this technology.
Purpose of the Study:
- To evaluate the accuracy of the Nexfin monitor for noninvasive arterial pressure (NAP) measurement.
- To compare NAP readings with traditional auscultatory blood pressure measurements (Riva-Rocci/Korotkoff, RRK).
Main Methods:
- NAP was measured in supine subjects and compared to RRK measurements.
- Two observers performed RRK measurements using an electronic stethoscope.
- Bias and precision of NAP-RRK differences were calculated for systolic and diastolic BP.
Main Results:
- A total of 312 data sets from 104 subjects were analyzed.
- Systolic BP (RRK) averaged 129 mmHg; diastolic BP averaged 80 mmHg.
- Median NAP-RRK differences were 5.4 mmHg (systolic) and -2.5 mmHg (diastolic), with good within-subject precision.
Conclusions:
- The Nexfin monitor demonstrates accurate BP measurement capabilities.
- The device offers good within-subject precision compared to RRK.
- Nexfin is a reliable tool for continuous, noninvasive BP monitoring.
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