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Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.

Appendicitis-II: Diagnostic Studies and Management

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
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It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...

Assessment of the Abdomen III: Palpation

Assessment of the Abdomen III: Palpation

Palpation is a crucial tactile examination method for assessing abdominal organs and detecting conditions like tenderness, distention, masses, or fluid. It involves both light and deep palpation techniques, each serving specific diagnostic purposes. Light palpation helps identify tenderness and other surface-level indicators, while deep palpation locates and assess abdominal masses and organ boundaries. A skilled professional can gather valuable insights through palpation, including evaluating...

Appendicitis

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

Assessment of the Abdomen II: Percussion

Assessment of the Abdomen II: Percussion

Percussion is a fundamental technique used to assess the liver, spleen, and abdominal organs by tapping the abdomen and interpreting the resulting sounds. This method helps identify fluid, distention, and masses through variations in sound, such as the high-pitched tympany of air-filled areas and the dullness of solid masses. Understanding how to percuss these organs provides valuable information for healthcare professionals in diagnosing conditions early.
Percussion
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Nursing Assessment of the Genitourinary System II: Inspection and Palpation

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The nursing assessment of the genitourinary (GU) system involves a systematic inspection and palpation to identify abnormalities in the kidneys, bladder, and surrounding structures.InspectionMouth: Inspect for signs of kidney dysfunction, such as stomatitis (inflammation of the mouth) and ammonia breath, which may occur in advanced kidney disease due to the buildup of urea, breaking down into ammonia.Skin: Check for pallor, which could indicate anemia caused by kidney disease. Look for...

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Related Experiment Video

Updated: Jun 26, 2026

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

Published on: March 10, 2023

Upper abdominal mass with diagnostic dilemma.

M O Ali¹, M M Rashid, M Saifullah

¹Department of Surgery, Dhaka Medical College Hospital, Dhaka, Bangladesh.

Mymensingh Medical Journal : MMJ

|February 3, 2009

Summary

A rare gastrointestinal stromal tumor (GIST) presented as an abdominal mass in a 32-year-old. Diagnosis was confirmed via immunohistochemistry, and the patient responded well to targeted therapy.

Area of Science:

Gastroenterology
Surgical Oncology
Pathology

Background:

Gastrointestinal stromal tumors (GIST) are rare mesenchymal neoplasms.
Early GISTs often present with vague symptoms, leading to delayed diagnosis.

Observation:

A 32-year-old male presented with a 3-month history of a growing upper abdominal mass, pain, low-grade fever, and early satiety.
Physical examination revealed an irregular, firm, tender, and poorly mobile abdominal mass.
Imaging (USG, CT) showed a soft tissue mass in the left upper abdomen with hepatomegaly and a liver space-occupying lesion (SOL).

Findings:

Fine-needle aspiration (FNA) indicated cells of mesenchymal origin.
Surgical resection revealed a large, lobulated, myxomatous, and highly vascular gastric fundal mass.

Related Experiment Videos

Last Updated: Jun 26, 2026

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

Published on: March 10, 2023

Histopathology suggested leiomyosarcoma or GIST; CD117 immunostaining confirmed GIST.

Implications:

This case highlights the importance of considering GIST in the differential diagnosis of upper abdominal masses.
Timely diagnosis and appropriate immunohistochemical staining are crucial for accurate GIST classification.
Post-operative treatment with Imatinib demonstrated positive patient response and is a key therapeutic strategy for GIST.