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Related Experiment Video

Updated: Jun 26, 2026

The Measurement and Treatment of Suppression in Amblyopia

The Measurement and Treatment of Suppression in Amblyopia

Published on: December 14, 2012

Foveal function in children treated for amblyopia.

Pia Agervi¹, Maria Nilsson, Lene Martin

¹Department of Clinical Neuroscience, Ophthalmology and Vision, Karolinska Institute, St Erik's Eye Hospital, Stockholm, Sweden. pia.agervi@sankterik.se

Acta Ophthalmologica

|February 3, 2009

Summary

This study found that the rarebit fovea test (RFT) may offer unique insights into foveal function in children with treated amblyopia, revealing similarities between amblyopic and fellow eyes not detected by standard visual acuity tests.

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The Measurement and Treatment of Suppression in Amblyopia

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Published on: December 14, 2012

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Published on: January 14, 2020

Area of Science:

Ophthalmology
Pediatric Vision Science
Visual Neuroscience

Background:

Amblyopia, or

Purpose of the Study:

To evaluate foveal function in children treated for monocular amblyopia using three distinct assessment methods.
To compare the efficacy of conventional visual acuity (VA) tests with a novel foveal function test in amblyopic children.

Main Methods:

A cohort of 24 children with treated amblyopia and 25 age-matched controls underwent best corrected visual acuity (BCVA) testing using the standard decimal (KM) chart and the computerized TriVA method at varying contrast levels.
Foveal function was assessed using the rarebit fovea test (RFT), measuring the mean hit rate (MHR) with a unique stimulus presentation (small, bright dots on a dark background).

Main Results:

Amblyopic eyes demonstrated significantly lower BCVA compared to fellow and control eyes across both KM chart and TriVA testing at different contrasts.
The RFT revealed no statistically significant difference in MHR between amblyopic and fellow eyes, though both were lower than controls.
RFT results suggest it may provide different information on foveal function compared to conventional VA tests.

Conclusions:

Findings align with existing literature indicating visual system disturbances in the fellow eyes of previously treated amblyopic patients.
The results suggest a potential generalized visual system disruption rather than solely monocular adaptation to refractive error or ocular motor issues.