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Updated: Jun 25, 2026
11:02
Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy
Published on: April 13, 2022
Root formation of an autotransplanted tooth
Luis Filipe Siu Lon1, Bruno Bochnia Cerci, Fernanda Brasil Baboni
1Dentistry Graduate Program, Orthodontics, Pontifical Catholic University of Paraná, Curitiba, Brazil
Summary
Autotransplantation of a premolar successfully restored a lost central incisor in a child, achieving root formation and periodontal healing. This dental trauma treatment offers a viable alternative to prosthetics or implants.
Area of Science:
- Dentistry
- Oral Surgery
- Regenerative Medicine
Background:
- Traumatic anterior tooth loss is common in children.
- Treatment requires careful consideration of biological, functional, esthetic, and economic factors.
Observation:
- A case report details the autotransplantation of a maxillary second premolar into the site of a missing maxillary right central incisor.
Findings:
- Successful root formation and periodontal healing were achieved post-autotransplantation.
- This procedure demonstrates significant regenerative potential in treating dental avulsion.
Implications:
- Tooth autotransplantation presents a viable alternative to conventional prosthetic and implant rehabilitation for traumatic dental injuries.
- This approach may improve long-term outcomes and patient quality of life.
Related Concept Videos
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The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
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01:15Teeth
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In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
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