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Study of Short Peptide Adsorption on Solution Dispersed Inorganic Nanoparticles Using Depletion Method
Published on: April 11, 2020
A simple method for the prevention of non-specific adsorption by nanocrystals onto surfaces
Carlos A Fernandez1, Robert J Wiacek, Ponnusamy Nachimuthu
1Pacific Northwest National Laboratory, P.O. Box 999, Richland, WA 99352, USA.
Abstract:
In this work we introduce an efficient method for averting non-specific adsorption of various nanoparticles to typical oxide surfaces, such as glass, quartz, and sapphire, through the attachment of a fluorinated self-assembled monolayer (SAM) that minimizes the interactions between stabilized nanoparticles and these surfaces. This surface treatment is shown to be effective for a variety of nanoparticles in a range of solvent systems. As a result, monitoring and characterization of nanoparticles and their surface chemistry is allowed, while simultaneously preventing loss of expensive nanomaterials to the various surfaces inherent in laboratory apparatus.

