Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

DNA Isolation

DNA Isolation

DNA isolation protocols can be fast and straightforward or complex and time-consuming depending on the type and quality of DNA required for further processing. For example, plasmid DNA extraction is a bit more complicated than genomic DNA extraction because of the need for an appropriate lysis method to separate plasmid DNA from gDNA during isolation. However, for specific applications, such as long-range DNA sequencing that require a good yield of high- quality DNA samples, we need to follow...

DNA Isolation

DNA Isolation

DNA from cells is required for many biotechnology and research applications, such as molecular cloning. To remove and purify DNA from cells, researchers use various methods of DNA extraction. While the specifics of different protocols may vary, some general concepts underlie the process of DNA extraction.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Nanochemical modulation of ECM-driven pseudo-resistance: convergent microenvironmental pathways in COVID-19 and cancer.

Chemical communications (Cambridge, England)·2026

Same author

Concept of 2D van der Waals Nanohybrids for Key Biomedical Applications.

International journal of nanomedicine·2026

Same author

Polyethyleneimine-functionalized MXene as stable two-dimensional platforms for gene delivery systems.

Chemical communications (Cambridge, England)·2026

Same author

Nanoengineered Niclosamide as a Microenvironment Modulator for Spinal Cord Regeneration: A Hypothetical Roadmap Toward Brain/Head Transplant Feasibility.

Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology·2026

Same author

Strategic Preparedness of Broad-Spectrum Antivirals for Rapid Response Towards Next Pandemics.

Small science·2026

Same author

Solvent mediated hierarchically porous NiCo-LDH decorated with Au nanoparticles for catalytic platforms.

Chemical communications (Cambridge, England)·2026

Search research articles

Related Experiment Video

Updated: Jun 25, 2026

Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures

Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures

Published on: January 19, 2019

Fe3O4@polypyrrole core-shell nanohybrid for efficient DNA retrieval.

Dae-Hwan Park¹, Jae-Min Oh, Yong-Gun Shul

¹Center for Intelligent Nano-Bio Materials (CINMB), Division of Nano Sciences BK21, Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea.

Journal of Nanoscience and Nanotechnology

|February 10, 2009

Summary

Superparamagnetic iron oxide Fe3O4@PPY nanohybrids were synthesized for DNA retrieval. These nanohybrids show high efficiency in capturing low-concentration DNA solutions.

More Related Videos

Single-Molecule Surface-Enhanced Raman Scattering Measurements Enabled by Plasmonic DNA Origami Nanoantennas

Single-Molecule Surface-Enhanced Raman Scattering Measurements Enabled by Plasmonic DNA Origami Nanoantennas

Published on: July 21, 2023

DNA-magnetic Particle Binding Analysis by Dynamic and Electrophoretic Light Scattering

DNA-magnetic Particle Binding Analysis by Dynamic and Electrophoretic Light Scattering

Published on: November 9, 2017

Related Experiment Videos

Last Updated: Jun 25, 2026

Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures

Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures

Published on: January 19, 2019

Single-Molecule Surface-Enhanced Raman Scattering Measurements Enabled by Plasmonic DNA Origami Nanoantennas

Single-Molecule Surface-Enhanced Raman Scattering Measurements Enabled by Plasmonic DNA Origami Nanoantennas

Published on: July 21, 2023

DNA-magnetic Particle Binding Analysis by Dynamic and Electrophoretic Light Scattering

DNA-magnetic Particle Binding Analysis by Dynamic and Electrophoretic Light Scattering

Published on: November 9, 2017

Area of Science:

Materials Science
Biotechnology
Nanotechnology

Background:

Developing efficient methods for DNA retrieval is crucial for various applications.
Nanomaterials offer unique properties for molecular capture and separation.

Purpose of the Study:

To synthesize and characterize a novel core-shell nanohybrid for DNA retrieval.
To evaluate the DNA uptake efficiency of the synthesized nanohybrid.

Main Methods:

Free radical polymerization was employed to synthesize the Fe3O4@PPY core-shell nanohybrid.
The nanohybrid's superparamagnetic properties stem from the Fe3O4 core, while polypyrrole provides DNA affinity.

Main Results:

The Fe3O4@PPY nanohybrid was successfully synthesized.
High DNA retrieval efficacy was observed, with approximately 33% uptake in a 100 microM DNA solution.
The nanohybrid demonstrated significant potential for capturing low-concentration DNA.

Conclusions:

The Fe3O4@PPY core-shell nanohybrid is a promising material for efficient DNA retrieval.
Its superparamagnetic nature facilitates easy separation, and the polypyrrole shell enhances DNA binding.
This nanohybrid offers a viable solution for applications requiring DNA capture from dilute solutions.