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Updated: Jun 25, 2026
14:21
Optical Frequency Domain Imaging of Ex vivo Pulmonary Resection Specimens: Obtaining One to One Image to Histopathology Correlation
Published on: January 22, 2013
[Excavated pulmonary opacity in diabetes]
Annales D'Endocrinologie
|February 10, 2009
Summary
Pulmonary mucormycosis, a fungal infection, affects immunocompromised individuals, particularly those with diabetes. Early diagnosis and treatment with amphotericin B are crucial for improving outcomes in this serious condition.
Area of Science:
- Mycology
- Infectious Diseases
- Pulmonology
Background:
- Mucormycosis, a zygomycete infection, primarily affects patients with uncontrolled diabetes or immunodepression.
- Increased incidence linked to immunosuppressive therapies and lack of effective antifungal prophylaxis against mucors.
Observation:
- A diabetic patient presented with a non-resolving excavated opacity in the right lung despite antibiotic treatment.
- Direct examination of bronchial washing confirmed pulmonary mucormycosis.
Findings:
- Pulmonary mucormycosis diagnosis confirmed via direct examination of bronchial washings.
- Early diagnosis is critical for effective treatment with amphotericin B.
Implications:
- High mortality rate (around 80%) emphasizes the need for prompt diagnosis and intervention.
- Diagnosis is often delayed, frequently occurring post-mortem, highlighting diagnostic challenges.
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